Çз ¹× ÁÖ¿ä°æ·Â
1985.3.-1991.4. Çѱ¹ÈÇבּ¸¿ø »ý¹°°øÇבּ¸½Ç(º´¿ªÆ¯·Ê¿¬±¸¿ø)
1988.8.-1988.12. The Kitasato Institute, Anticancer Lab.(UNDP¿¬±¸¿ø)
1991.4.-1991.9. Univ. of Tokyo, Graduate School of Pharmaceutical Sci.(¿¬±¸»ý)
1991.10.-1995.9. Univ. of Tokyo, Graduate School of Pharmaceutical Sci.(¹Ú»ç°úÁ¤) Identification and characterization of apoptotic soluble factors produced by lymph node stromal cells (Prof. Takashi Tsuruo)
1995.9.-1996.9. Univ. of Tokyo, Inst. Cell. Mol. Biosci. (postdocoral fellow)
1996.9.-1997.9. Columbia Univ. Coll. of Physicians & Surgeons, Div. of Med. Oncol.(postdocoral scientist)
1997.9.-1999.3. Rockefeller University, Lab of Immunol. (postdoctoral associate)
2000.3.-2005.1. Çѱ¹»ý¸í°øÇבּ¸¿ø ¹ÙÀÌ¿À½Å¾à¿¬±¸ºÎ(Ã¥ÀÓ¿¬±¸¿ø)
2001.3-2005.3. °ú±âºÎ, »êÀÚºÎ, ³ó¸²ºÎ, º¸º¹ºÎ, ȯ°æºÎ ¿¬±¸»ç¾÷ (±âȹ ¶Ç´Â Æò°¡ À§¿ø)
2005.2 - ÇöÀç °æºÏ´ëÇб³ ½ÄÇ°°øÇаú È¿¼Ò»ý¹°°øÇдã´ç(Á¶±³¼ö)
22³â 9¿ù ÇöÀç Food Chemistry, Arabian Journal of Chemistry, Ultrasonics Sonochmistry, Process Biochemistry¿¡ Åõ°í Áß
´ëÇ¥³í¹® Alam MB, Majumder R, Kim SH, Lee SH. Attenuation of melanogenesis by Nymphaea nouchali (Burm. f) flower extract through the regulation of cAMP/CREB/MAPKs/MITF and proteasomal degradation of tyrosinase. Sci Rep, 8, 13928, 2018. Sep. 17
¡° Áֿ俬±¸¾÷Àû ¡± ´ëÇ¥³í¹®
1. Lee, D.S., and Lee, S.-H. (2001) Genistein, a soy isoflavone, is a potent alpha-glucosidase inhibitor. FEBS Lett.,501, 84-86.
2. Lee, S.-H., Youk, E.S., Jeon, Y.J., Han, S.B., Kim, H.C., and Kim, H.M. Polychlorinated biphenyls activate caspase-3-like death protease in vitro, but not in vivo. (2001) Biol. Pharm. Bull.24, 1380-1383.
3. Lee, S.-H., Lee, C.W., Hong, D.H., Han, S.B., Kim, H.C., Fine, R.L., and Kim, H.M. A novel stereo-selective sulfonylurea, 1-(1-Benzoylindoline-5-sulfonyl)-4-phenyl -4,5-dehydroimidazolones has antitumor efficacy in in vitro and in vivo tumor models. (2002) Biochem. Pharmacol., 64, 473-480.
4. Lee, S.-H., Chang, K.T., Kwon, O.Y., and Kwon, T.K. Etoposide activates caspase-3 via a caspase-1-independent mechanism in cancer cells. (2002) Exp. Oncol., 24,105-107.
5. Kim, H.J., Moon, K.D., Lee, D.-S., and Lee, S.-H. (2003) Ethyl ether fraction of Gastrodia elata Blume protects amyloid beta peptide-induced cell death. J. Ethnopharmacol. 84, 95-98.
6. Lee, S.-H.,Youk, E.S., Lee, H.J., Kho, Y.H., Kim, H.M., and Kim, S.-U. Dykellic acid inhibits camptothecin-induced caspase-3 protease activation. (2003) Biochem. Biophys. Res. Commun., 302, 539-544.
7. Woo, J-H., Park, J-W., Lee, S-H., Kim, Y-H., Lee, I. K., Gabrielson, E., Lee, S.-H., Lee, H.-J., Kho, Y.-H., and Kwon, T. K. (2003) Dykellic Acid Inhibits Phorbol Myristate Acetate-induced Matrix Metalloproteinase-9 Expression by Inhibiting NF-kB Transcriptional Activity. Cancer Res., 63, 3430-3434.
8. Hwang, Y. K., Chun, J.S., Yoo, P. D., Ma, J. Y., Hyun, B. H., Kim, S. U. Chang, K. T., and Lee, S. H. Occlusal reduction of unilateral molars influences change of stress-related hormones in rats. Scad. J. Lab Animal Sci., 31(2), 73-77 (2004).
9. Moon, S.-H., Heo, J.C., Fine, R.L., Kim, S.-U., Lee, S.-H. (2005) BRD-glucan exhibits potent immunochemotherapeutic activity in vitro and in vivo, Int. J.Oncol., 26, 395-404.
Byeon JH, Joung O, Lee HY, Shin JC, Choi WS, Lee TH, Hwang JS, Nam SH, Son HU, Lee SH. Anti-melanogenic effects by chestnut spike extract through downregulation of tyrosinase-related proteins and activation of ERK 1/2. Nat Prod Commun, 13(X), XXX-XXX, 2018. (IF=0.809)
Bajpai VK, Alam MB, Ju MK, Kwon KR, Huh YS, Han YK, Lee SH. Antioxidant mechanism of polyphenol-rich Nymphaea nouchali leaf extract protecting DNA damage and attenuating oxidative stress-induced cell death via Nrf2-mediated heme-oxygenase-1 induction coupled with ERK/p38 signaling pathway. Biomed Pharmacother, 103, 1397-1407. (IF=3.457)
Bajpai VK, Alam MB, Quan KT, Choi HJ, An H, Ju MK, Lee SH, Huh YS, Han YK, Na MK. Cytotoxic properties of the anthraquinone derivatives isolated from the roots of Rubia philippinensis. BMC Compl Altern Med, 18, 200, 2018. (IF=2.288)
Bajpai VK, Alam MB, Quan KT, Ju MK, Majumder R, Shukla S, Huh YS, Na MK, Han YK, Lee SH. Attenuation of inflammatory responses by (+)-syringaresinol via MAP-kinase-mediated suppression of NF-kB signaling in vitro and in vivo. Sci. Rep., 8, 9216, 2018. June 15 (IF=4.122)
Baek SH, Joung O, Lee HY, Shin JC, Choi WS, Lee TH, Hwang JS, Nam SH, Son HU, Lee SH. Anti-oxidative Fraction of Lycorma delicatulaAlleviates Inflammatory Indicators. Nat Prod Commun, 13(4), 431-434, 2018. (IF=0.809)
Hwang IW, Kim BM, Kim YC, Lee SH., Chung SK Improvement in ¥â-glucan extraction from Ganoderma lucidum with high-pressure steaming and enzymatic pre-treatment. Appl Biol Chem, 61, 235-242, 2018. (IF=1.362)
Peijun Zhao, Md Badrul Alam, Hongyan An, Hee-Jeong Choi, Yeong Ho Cha, Chi-Yeol Yoo, Hyo-Hyun Kim, Sang-Han Lee. Antimelanogenic effect of an Oroxylum indicumseed extract by suppression of MITF expression through activation of MAPK signaling protein. Int J Mol Sci, 19(3), 760, 2018 (IF=3.687)
Rahmana MS, Choi YH, Choi YS, Alam MB, Lee SH, Yoo JC. A novel antioxidant peptide, purified from Bacillus amyloliquefaciens, showed strong antioxidant potential via Nrf-2 mediated heme oxygenase-1 expression. Food Chem., 239, 502-510 (2018) Jan 15, 2018. (IF=4.946)
Alam MB, Bajpai VK, Lee JI, Zhao P, Byeon JH, Ra JS, Majumder R, Lee JS, Yoon JI, Rather IA, Park YH, Kim K, Na M, Lee SH.Inhibition of melanogenesis by jineol from Scolopendra subspinipes Mutilans via MAP-kinase mediated MITF downregulation and the proteasomal degradation of tyrosinase. Sci. Rep., 7, 45858, 2017.
Bajpai VK, Alam MB, Quan KT, Kwon KR, Ju MK, Choi HJ, Lee JS, Yoon JI, Majumder R, Kim K, Lee SH, Na M. Antioxidant efficasy and the upregulation of Nrf2-mediated HO-1 expression by (+)-Lariciresinol, a lignan isolated from Rubia philippinensis, through the activation of p38. Sci. Rep., 7, 46035, 2017.
Seo SU, Cho HK, Min KJ, Woo SM, Kim S, Park JW, Kim SH, Choi YH, Keum YS, Hyun JW, Park HH, Lee SH, Kim DE, Kwon TK. Thioridazine enhances sensitivity to carboplatin in human head and neck cancer cells through downregulation of c-FLIP and Mcl-1 expression. Cell Death Dis. 8(2):e2599, 2017.
Alam MB, Kwon KR, Lee SH, Lee SH. Lannea coromandelica (Houtt.) Merr. Induces Heme Oxygenase 1 (HO-1) Expression and Reduces Oxidative Stress via the p38/c-Jun N-Terminal Kinase-Nuclear Factor Erythroid 2-Related Factor 2 (p38/JNK-NRF2)-Mediated Antioxidant Pathway. Int J Mol Sci. 18(2), E266, 2017.
Hyeng-U Son, Yong-Kyu Shin, Jong-Myung Kim, Sang-Han Lee. Solid Fermentation with Phellinus baumii Improved Anti-Atopic Effect on Aqueous Fraction of Cinnamomum cassia. 2015³âµµ Çѱ¹½ÄÇ°ÀúÀåÀ¯ÅëÇÐȸÁ¤±âÇмú´ëȸ, Á¦ÁÖ´ëÇб³ ±¹Á¦±³·ùȸ°ü, 2015³â10¿ù22ÀÏ~10¿ù23ÀÏ. ¿ì¼öÆ÷½ºÅÍ»ó ¼ö»ó
[¾ð·Ðº¸µµ] MBC »ý¹æ¼Û¿À´Ã¾Æħ (°¨¹°¿°»ö), ¿ÀÀü8½Ã30ºÐ, 2015.10.20.
Shin DK, Kim MH, Lee SH, Kim TH, Kim SY. Inhibitory effects of luteolin on titanium-particle-induced osteolysis in a mouse model. Acta Biomateria, 8, 3524-3531, 2012.